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Endochondroma (chondroma, Ollier's disease)

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What is Endochondroma?

Chondroma is a benign (does not spread throughout body) tumour of cartilage. When chondromas form within the medullary cavity within the bone they are called endochondromas. Olliers disease is a syndrome when a person suffers from many endochondromas.

Who gets Endochondroma?

Chondromas mainly affects people between the age of 10 and 30 years. There is an equal incidence of chrondomas between males and females.

Predisposing Factors

Olliers disease is caused by an inborn genetic error that causes abnormal endochondral bone formation. The cause of single endochondromas is unknown.

Progression

Endochondromas have the potential to become malignant chondrosarcomas. In Olliers disease 30% of patients have malignant transformation. Overall 1% of endochondromas undergo malignant transformation. Tumours closer to the midline are more likely to become malignant.

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calendar icon Created: 30/12/2003 calendar icon Modified: 6/2/2008
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