Drugs
Gemzar
Generic Name: Gemcitabine hydrochloride
Product Name: Gemzar
- Indication of Gemzar
- Action of Gemzar
- Dose Advice of Gemzar
- Schedule of Gemzar
- Common side effects of Gemzar
- Uncommon side effects of Gemzar
- Reference
Indication of Gemzar:
Treatment of the following locally advanced, metastatic or non responsive cancers:- Non-small cell lung cancer
- Pancreatic adenocarcinoma
- Bladder cancer
- Breast cancer
- Ovarian carcinoma
Action of Gemzar:
Gemciabine targets and kills cancer cells. It does this by damaging the DNA within the cell rendering it incapable of dividing.Dose Advice of Gemzar:
Gemcitabine is administered intravenously.The dose and administration regime varies with cancer type, combination therapy, hepatic and renal insufficiency and age of the patient.
In general, a dose of approximately 1,000 mg/m2 is given over a 30-minute period. This is repeated weekly or monthly during the designated treatment period.
Gemcitabine may cause drowsiness, do not drive or operate heavy machinery if affected.
Schedule of Gemzar:
S4Common side effects of Gemzar:
- Low platelet and immune cell count.- Anaemia.
- Drowsiness.
- Shortness of breath.
- Nausea.
- Vomiting.
- Diarrhoea.
- Constipation.
- Allergic skin rash.
- Hair loss.
- Itchness.
- Ulceration of mucous membrane of the mouth.
- Blood or protein in the urine.
- Swelling.
- Flu like symptoms.
- Fever.
- Weakness.
- Raised Liver function tests.
Uncommon side effects of Gemzar:
- Allergic reactions.- Heart failure or arrhythmia.
- Low blood pressure.
- Lung dysfunction.
- Changes in the skin.
- Kidney failure.
- Cough.
- Colds.
- Perspiration.
- Sleeping difficulties.
Reference:
[1] MIMS Australia Pty Ltd [online]. Gemzar. MediMedia: NSW; 2005.Diseases treated by Gemzar:
- Breast Cancer (Pre-Invasive Ductal Carcinoma; Ductal Carcinoma In Situ; DCIS)
- Carcinoma of the Breast
- Lung Cancer (Adenocarcinoma of the Lung)
- Pancreatic Cancer (Adenocarcinoma of the Pancreas)
Regimens that include Gemzar:
For further information talk to your doctor.
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