Drugs
Lucrin
Generic Name: Leuprorelin acetate
Product Name: Lucrin
- Indication of Lucrin
- Action of Lucrin
- Dose Advice of Lucrin
- Schedule of Lucrin
- Common side effects of Lucrin
- Uncommon side effects of Lucrin
- Reference
Indication of Lucrin:
Lucrin (leuprorelin acetate) is a drug that is currently used to treat advanced cancer of the prostate gland, as well as other hormonal conditions affecting the reproductive organs including- Endometriosis
- Uterine fibroids
- Endometrial thinning
- Advanced breast cancer in premenopausal women
- Precocious puberty
Action of Lucrin:
Lucrin (Leuprorelin) is a drug that mimics the action of a hormone called gonadotrophin releasing hormone. This hormone when present in the body stimulates the production of sex steroids by the reproductive organs, the ovary and the testes. The key to the normal function of this hormone is the fact that it is released in pulses. But when used as a drug for long periods of time, the levels of this artificial hormone become consistently high. This has the effect of causing reduced production of hormones by the reproductive organs, and it is this effect that is believed to cause a reduction in tumour growth in people with advanced prostate cancer.Dose Advice of Lucrin:
Lucrin is given via an injection into the fatty tissue under the skin (subcutaneous). The doctor will change the site of injection regularly.Schedule of Lucrin:
S4Common side effects of Lucrin:
- hot flushes
- sweating
- loss of menstruation (amenorrhoea)
- withdrawal bleeding
- sexual dysfunction
- reduced libido
- vaginal dryness
- changes in breast size breast tenderness
- joint pains (arthralgia)
- muscle pains (myalgia)
- peripheral oedema
- dizziness
- headache
- nausea
- vomiting
- constipation
- mood changes
- injection site reaction
- thrombophlebitis - inflammation of a vein with an associated blood clot
- decreased bone mass
Uncommon side effects of Lucrin:
- Bronchospasm (contraction and narrowing of the airways in the lungs)
- Rash
- Altered sensation (paraesthesia)
- depression
Reference:
- 'Leuprorelin' [online], AMH, 2006, Available at URL: http://www.amh.net.au (last accessed 31/07/2006)
- 'Lucrin Prescribing information' [online], MIMS, 2006, Available at URL: http://www.mims.com.au (last accessed 31/07/2006)
Diseases treated by Lucrin:
For further information talk to your doctor.
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