Tramal

Drugs

Generic Name: Tramadol hydrochloride
Product Name: Tramal

Indication of Tramal
Action of Tramal
Dose Advice of Tramal
Schedule of Tramal
Common side effects of Tramal
Uncommon side effects of Tramal

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Indication of Tramal:

Tramal is a strong painkiller used in the treatment and prevention of moderate to severe pain.

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Action of Tramal:

This medicine contains the active ingredient tramadol hydrochloride, which is a type of medicine called an opioid analgesic or painkiller. Opioid painkillers work by mimicking the action of naturally occurring pain-reducing chemicals called endorphins. Endorphins are found in the brain and spinal cord and reduce pain by combining with opioid receptors. Tramadol mimics the action of our natural endorphins by combining with the opioid receptors in the brain and spinal cord. This blocks the transmission of pain signals sent by the nerves to the brain. Therefore, even though the cause of the pain may remain, less pain is actually felt. Tramadol also works by enhancing the activity of neurotransmitters in the brain and spinal cord. Neurotransmitters are chemical compounds that act as chemical messengers between the nerve cells. Tramadol enhances the effect of the neurotransmitters serotonin and noradrenaline, and this action also helps relieve pain.

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Dose Advice of Tramal:

The dose of Tramal should be titrated according to the severity of the pain and the clinical response of the patient. Tramal comes in many formulations and therefore the recommended dosage is as follows:

Tramal Capsules: Administered orally. For moderate pain an initial dose of 50mg may be adequate. Then maintain relief by a dose of 50 to 100mg taken two to three times daily.For moderate to severe pain, 100mg is effective as an initial dose. Maintenance dosing of 50 to 100mg every four to six hours may then be given up to a maximum daily dose of 400mg.

Tramal solution for injection: Administered parenterally, by IM or IV injection. For postoperative pain an initial bolus dose of 100mg should be administered. Subsequent doses of 50 to 100mg every four to six hours may be given, up to a maximum daily dose of 600mg. For less severe pain, 50 or 100mg every four to six hours up to a maximum daily dose of 400mg.

Tramal SR tablets:Administered orally. The recommended dose is 100 to 200mg twice daily, preferably in the morning an evening. Tablets should be taken as a whole with sufficient liquid. However maximum daily dose should not exceed 400mg.

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