Paclitaxel

Used For:

Paclitaxel is used for:
  • Stage IV breast cancer, as third line therapy.
  • Metastatic ovarian cancer after standard therapy has failed.
  • Secondary treatment of non-small cell lung cancer.

Overview:

Paclitaxel is an antimetabolite agent known as a taxane. Taxanes interfere with the formation of microtubules, structures in the cell that are vital for cell division. Paclitaxel causes the formation of dysfunctional microtubules that cannot be dismantled by the cell. Unable to divide, the cell is stranded mid-cycle and dies. Paclitaxel can be used alone, as described here, or in combination with other chemotherapeutic agents.

Constituents:


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Article Dates:

Created: 12/5/2006 Modified: 29/5/2008
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